Infrequent microsatellite instability in liver fluke infection-associated intrahepatic cholangiocarcinomas from Thailand

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Infrequent microsatellite instability in liver fluke infection-associated intrahepatic cholangiocarcinomas from Thailand.

The liver fluke infection-associated intrahepatic cholangiocarcinoma (ICC) is a major liver cancer in Northeast Thailand. The molecular basis of this ICC is poorly understood. To address possible roles of the DNA mismatch repair (MMR) system in ICC carcinogenesis, a fluorescence-labeling PCR/laser scanning technique with high sensitivity was employed to analyze genomic instability in the nuclea...

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cholangiocarcinoma associated with liver fluke infection in an iranian patient

biliary liver flukes are common parasites in some regions of the world where consumption of raw fresh-water fish is a cultural practice. clonorchis sinensis and opisthorchis species are the major biliary liver flukes associated with human disease. some of these parasites are highly associated with cholangiocarcinoma. this report describes a clinically and epidemiologically unsuspected liver flu...

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ژورنال

عنوان ژورنال: International Journal of Cancer

سال: 2003

ISSN: 0020-7136,1097-0215

DOI: 10.1002/ijc.11380